Postdoc Profile: Gabriel Abuna

Gabriel Abuna
abunag20@ecu.edu
Foundational Sciences
School of Dental Medicine

Mentors
Ramiro Murata
Saulo Geraldeli

Education
PhD, State University of Campinas
MSc, State University of Campinas

Research Summary
My primary research is to understand how HIV replication, continued cellular reinfection, and persistence depend on the regulation of transcription factors and anti-viral restriction factors associated with target cell activation and the cytokine microenvironment. Understanding the effects of oral Candida spp on HIV pathogenesis will establish a means by which the mycobiome contributes to the modulation of host viral restriction factors. Besides, I also design nanoparticles with high flexibility for smart delivery and tailored treatments. We have been perfectionating, enhancing, and optimizing its synthesis. I aim to use these nanoparticles over mineralizing cells to understand enough to be tailored for regenerative therapies.